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Cajun Chicken Alfredo Pasta

Recipe by lifewithmarq on InstagramAdded 21 September 2026.
  • 30 min
  • Serves 2
  • 9 ingredients

10 minutes to prep, 20 to cook. A creamy Cajun chicken alfredo that blends smoky Cajun spice with a rich, velvety Parmesan cream sauce. Served over a mix of penne and fettuccine, it makes a satisfying dinner for two.

See all 8 versions of chicken Alfredo, compared

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Ingredients

2 servingsMetric

Amounts as lifewithmarq gives them. Metric converts supported weights and liquids, and oven temperatures; spoon measures and counts stay as written.

Method

  1. 1

    Season the chicken thighs on both sides with Cajun seasoning and a pinch of salt.

  2. 2

    Heat a large skillet over medium‑high heat, add a little oil if needed, and sear the chicken thighs until golden brown, about 6–7 minutes per side. Transfer to a plate, let rest briefly, then slice into strips.

    Kitchen notes · Added by ReelsMeals: The chicken has a golden surface before it rests and is sliced.

  3. 3

    In the same skillet, melt the butter over medium heat and add the minced garlic. Cook, stirring constantly, for about 30 seconds until fragrant but not browned.

  4. 4

    Pour in the heavy cream and stir to combine with the garlic butter. Bring to a gentle simmer, then add the grated Parmesan cheese. Continue stirring until the sauce thickens and coats the back of a spoon, about 3–4 minutes.

    Kitchen notes · Added by ReelsMeals: The Parmesan melts into a sauce that coats the back of a spoon.

  5. 5

    While the sauce is thickening, bring a large pot of salted water to a boil. Cook the penne and fettuccine together according to package directions until al dente, then drain, reserving a splash of pasta water.

  6. 6

    Add the cooked pasta to the skillet with the Alfredo sauce, tossing to coat evenly. If the sauce is too thick, thin it with a little reserved pasta water.

    Kitchen notes · Added by ReelsMeals: The pasta is evenly coated and the sauce stays silky after tossing.

  7. 7

    Stir the sliced Cajun chicken into the pasta, mixing gently to distribute the meat throughout.

  8. 8

    Transfer the pasta to serving plates, garnish with chopped parsley (if using), and serve immediately.

Tips while you cook

Rest chicken before slicing
After searing, let the chicken thighs rest briefly before cutting into strips.
Reserve pasta water
Save a splash of the pasta cooking water to thin the Alfredo sauce if needed.
Briefly cook garlic
Sauté the minced garlic for about 30 seconds until fragrant, avoiding browning.

Notes from ReelsMeals, based on this recipe's ingredients, times and method. They are not the creator's instructions.

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lifewithmarq made this.

The recipe comes from lifewithmarq’s Instagram reel. ReelsMeals wrote it down from the caption and the voiceover. Check the original if something looks off, and for anything about allergens.

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Chicken Alfredo, 8 ways

Eight creators posted their own. Most use chicken, garlic and parmesan cheese.

  1. Christopher Smith30 min12 ingr.Only this one uses pasta and chicken broth
  2. Matthew Bounds55 min9 ingr.Only this one uses rotisserie chicken, penne pasta and mozzarella cheese
  3. lifewithmarq30 min9 ingr.Only this one uses penne, fettuccine and heavy cream
  4. rileysstupidrecipes1 hr5 ingr.Only this one uses lower-calorie alfredo sauce
  5. cookingforgains50 min7 ingr.Only this one uses ground chicken, kinder's salt and bell pepper
  6. lindshampton1 hr14 ingr.Only this one uses cottage cheese and garlic and herb laughing cow cheese wedges
Compare all 8 side by side

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    • Dinner
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